Since 2017, Colorado and Iowa State have met 1 time, with Colorado holding a 1–0 edge in the series.
Most recently Colorado won 24–17 on October 11, 2025.
Right now Colorado is 2–3 and Iowa State is 3–2, with Colorado at 24 days since a win against Iowa State's 3.
| Date | Site | Winner | Score |
|---|---|---|---|
| Sat, Oct 11 2025 | Colorado home | Colorado | 24–17 |
Full schedules and drought counters: Colorado Buffaloes and Iowa State Cyclones.
Colorado vs Arizona, Colorado vs Arizona State, Colorado vs Baylor, Colorado vs BYU, Colorado vs Cincinnati, Colorado vs Houston, Colorado vs Kansas, Colorado vs Kansas State, Colorado vs Oklahoma State, Colorado vs TCU, Colorado vs Texas Tech, Colorado vs UCF, Colorado vs Utah, Colorado vs West Virginia.
Iowa State vs Arizona, Iowa State vs Arizona State, Iowa State vs Baylor, Iowa State vs BYU, Iowa State vs Cincinnati, Iowa State vs Houston, Iowa State vs Kansas, Iowa State vs Kansas State, Iowa State vs Oklahoma State, Iowa State vs TCU, Iowa State vs Texas Tech, Iowa State vs UCF, Iowa State vs Utah, Iowa State vs West Virginia.