Since the 2017–18 season, Clemson and Louisville have met 12 times and split them evenly at 6–6.
Most recently Clemson won 80–75 on February 28, 2026.
Right now Clemson is 0–0 and Louisville is 0–0, with Clemson at 208 days since a win against Louisville's 201.
| Date | Site | Winner | Score |
|---|---|---|---|
| Sat, Feb 28 2026 | Clemson home | Clemson | 80–75 |
| Fri, Mar 14 2025 | Neutral site | Louisville | 76–73 |
| Tue, Jan 7 2025 | Louisville home | Louisville | 74–64 |
| Tue, Jan 30 2024 | Clemson home | Clemson | 70–64 |
| Sat, Feb 18 2023 | Louisville home | Louisville | 83–73 |
| Wed, Jan 11 2023 | Clemson home | Clemson | 83–70 |
| Sat, Feb 19 2022 | Louisville home | Louisville | 70–61 |
| Wed, Jan 27 2021 | Clemson home | Clemson | 54–50 |
| Sat, Feb 15 2020 | Clemson home | Clemson | 77–62 |
| Sat, Jan 25 2020 | Louisville home | Louisville | 80–62 |
| Sat, Feb 16 2019 | Louisville home | Louisville | 56–55 |
| Sat, Jan 6 2018 | Clemson home | Clemson | 74–69 |
Full schedules and drought counters: Clemson Tigers and Louisville Cardinals.
Clemson vs Boston College, Clemson vs California, Clemson vs Duke, Clemson vs Florida State, Clemson vs Georgia Tech, Clemson vs Miami, Clemson vs NC State, Clemson vs North Carolina, Clemson vs Notre Dame, Clemson vs Pittsburgh, Clemson vs SMU, Clemson vs Stanford, Clemson vs Syracuse, Clemson vs Virginia Tech, Clemson vs Virginia, Clemson vs Wake Forest.
Louisville vs Boston College, Louisville vs California, Louisville vs Duke, Louisville vs Florida State, Louisville vs Georgia Tech, Louisville vs Miami, Louisville vs NC State, Louisville vs North Carolina, Louisville vs Notre Dame, Louisville vs Pittsburgh, Louisville vs SMU, Louisville vs Stanford, Louisville vs Syracuse, Louisville vs Virginia Tech, Louisville vs Virginia, Louisville vs Wake Forest.